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Methylene Blue
Updated 3/18/2026
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Cognitive
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Research Summary
Methylene Blue (MB) is a synthetic compound with a unique history. Originally synthesized as a textile dye in 1876, it became the first fully man-made medicine. While it is an FDA-approved treatment for a blood disorder called methemoglobinemia, low-dose Methylene Blue has recently surged in popularity as a biohacking and wellness supplement. In the longevity space, it is highly regarded as a potent nootropic (cognitive enhancer) and a mitochondrial optimizer due to its powerful cellular-level antioxidant properties.
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