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Magnesium L-threonate

Updated 3/11/2026
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Research Summary

Magnesium L-threonate is a specialized form of magnesium where the mineral is chelated with L-threonic acid, a metabolite of Vitamin C. Developed by a team of neuroscientists at MIT, it was designed specifically to overcome the low brain-bioavailability of traditional magnesium supplements. Unlike common forms such as magnesium oxide or citrate, L-threonate has a unique ability to cross the blood-brain barrier effectively, significantly elevating magnesium concentrations within the brain and cerebrospinal fluid.

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